Prof. Joe Tsien from U. S. Augusta University Will Give An Academic Report

By 吴婵Viewed 13 2020-01-02

Speaker: Prof. Joe Tsien from U. S. Augusta University

Theme: The Brain Decoding

Time:10:00, Jan. 10, 2020

Address: Yifu Multi-functional Hall, Liuyuan Hotel

  

About the speaker:

Professor Joe Tsien is an internationally renowned brain scientist. His Cre-lox neurogenetic technology pioneered at MIT and Princeton University, as well as the knockout and editing technology of permeability and brain-specific gene or protein, has established his position as a pioneer in genetics and genetic engineering. Besides, he’s also the authority on brain science, especially the study on learning mechanisms and neural networks; therefore, he’s renowned as “the father of clever rats” by TIME Magazine. His articles published in Nature, Science, Cell, Neuron, Nat Neurosci and other internationally renowned academic journals have been cited for more than 16,000 times. He has been granted the Distinguished Scholar Award by Keck Foundation, the Beckman Award, the Bolaus Wellcome Award, the Chinese American Outstanding Science Award and the US Army Chief Scientist Memorial Medal.

Professor Joe Tsien first initiated “the Brain Decoding Project” as the person in charge in 2007, which triggered the current brain project in Europe and the United States. He proposed the Theory of Connectivity regarding the principle of brain design and calculation, which has been verified in neural networks of a variety of animal brains and dozens of brain regions. This theory will provide a theoretical framework for the research and development of the new generation of artificial intelligence and robotics, especially the artificial general intelligence and brain-like chips.

  

Speaker: Dr. Chen Liangyi, Boya Chair Professor of Peking University

Theme: Super-microscope --- High time-space resolution microscopy of next-generation in vivo

Time:11:00, Jan. 10, 2020

Address: Yifu Multi-functional Hall, Liuyuan Hotel

  

About the speaker:

Dr. Chen Liangyi, Boya Chair Professor of Peking University, has been focusing on such key scientific issues as the abnormal insulin secretion mechanism during the onset of diabetes in the latest five years. His researches concern three specific issues, namely, the disorders of blood glucose regulation at the viable tissue level, the abnormal cell function at the cell level, and how the metabolism regulates the vesicle secretion at the molecular level. A series of visualization approaches for high time-space resolution biomedical imaging have been developed. The invention of high-resolution miniaturized two-photon microscope and two-photon three-axis scanning light sheet microscope, multi-angle total internal reflection microscope, low-sensitivity ultra-sensitive Hessian super-high-resolution SIM, etc. have solved many important problems in biology. The results were published in journals such as Nature Biotechnol, Nature Methods, Dev Cell and Cell Res. etc.; besides, such achievements were also screened as “Top Ten Progresses in Chinese Optics in 2018”, “Top Ten Progresses in Chinese Science in 2017” and 2018 Annual Method by Nature Method: “Free Behavior Animal Imaging technology”, etc..

  

Speaker: Dr. Sureshkumar Balasubramanian, Associate Professor, School of Biological Sciences, Monash University

Theme:A new approach for splicing analysis- potential and implications

Time:9:00, Jan. 10, 2020  

Address: Yifu Multi-functional Hall, Liuyuan Hotel

  

About the speaker:

Dr. Balasubramanian is interested in deciphering the mechanistic basis of genotype x environment interactions. His group focuses on three key areas. They are deciphering mechanisms through which plants sense and respond to changes in temperature using a combination of mutant analysis, natural variation and genomics. The second area is related to understanding molecular mechanisms of genetic diseases. Recently his group discovered a triplet repeat expansion associated genetic defect in Arabidopsis. Triplet expansions underlie several human genetic diseases such as Huntington's disease and Friedreichs ataxia. The Arabidopsis model shares striking similarities with the human situation at a molecular level. This provides an excellent genetic system to investigate fundamental aspects of repeat expansion associated genetic defects. They also have a particular interest in the analysis of splicing, trying to uncover the principles that govern splice site selection in organisms. To address these, they use a combination of model organisms such as Marchantia, Arabidopsis, fruit flies as well as humans. Their novel approach allows the determination of determinants of splice site selection and decipher the principles that govern splicing decisions. He published his work in many top journals such as Nature, Cell, Science, Nature Genetics, PNAS, PLoS Genetics, Current Biology, Plant Cellet al.